3+ day, 14+ hour ago  (211+ words) The genitourinary system undergoes a complex development, making it prone to congenital anomalies. M'llerian duct anomalies are among these, affecting the uterus, cervix, and vagina due to errors in ductal fusion or septal resorption during development. During cadaveric dissection of…...

5+ day, 14+ hour ago  (264+ words) Thioredoxin-related transmembrane protein 2 (TMX2)-related neurodevelopmental disorder (OMIM #618730) is an exceedingly rare autosomal recessive condition caused by biallelic pathogenic variants in TMX2, a gene encoding an endoplasmic reticulum (ER)-resident oxidoreductase involved in neuronal survival and cortical development. The condition is characterized…...

6+ day, 14+ hour ago  (386+ words) Introduction: Maternal anemia remains a major public health concern associated with adverse maternal and neonatal outcomes worldwide. Oral mucosal changes are also commonly observed in anemic individuals and may reflect the systemic severity of nutritional and hematological deficiencies. This study…...

1+ week, 1+ day ago  (398+ words) Introduction: Fetal sex is increasingly recognized as a biological variable that may influence placental development, fetal circulation, and pregnancy outcomes. However, sex-specific fetal Doppler data are limited in African populations. This study assessed whether Doppler indices of the umbilical artery…...

1+ week, 3+ day ago  (167+ words) We encountered a male infant with extremely low birth weight born at 22 weeks and 0 days of gestational age in the toilet at home. He was resuscitated with chest compression and bag-valve-mask ventilation by the emergency medical service crew and was…...

1+ week, 3+ day ago  (311+ words) Introduction Neonatal infections continue to pose major challenges in intensive care settings. This study aimed to evaluate the prevalence, maternal risk factors, neonatal characteristics, and clinical outcomes associated with early-onset neonatal septicemia in neonates admitted to the neonatal intensive care…...

1+ week, 4+ day ago  (312+ words) Introduction Numerous skin changes occur in pregnancy, the majority of which are physiological in nature and linked to the hormonal, metabolic, vascular, or immunologic changes. However, some pruritic eruptions cause anxiety during pregnancy and may affect the maternal and fetal…...

1+ week, 5+ day ago  (37+ words) Cureus Please note that by doing so you agree to be added to our monthly email newsletter distribution list. Download Cureus Media Kit...

1+ week, 5+ day ago  (270+ words) Craniorachischisis totalis is the most severe form of open neural tube defect and combines acrania/anencephaly with extensive open spinal dysraphism. It is rare, lethal, and usually identifiable prenatally, but diagnostic labeling may evolve across pregnancy as imaging findings become…...

1+ week, 6+ day ago  (280+ words) Acetaminophen (paracetamol, APAP) overdose is well characterized in pediatric and adult populations; however, reports of toxicity in premature neonates remain exceedingly rare. Existing literature describing acetaminophen overdose in preterm infants is limited to only four published cases. Acetaminophen metabolism in…...